Department of Pharmacology

Introduction to the Department:

Pharmacology is the study of the actions and fates of drugs and other chemical substances in biological systems. The Department of Pharmacology at College of Medicine -Nepalese Army Institute of Health Sciences(NAIHS) is one of the basic medical science departments established in 2011. The college is affiliated to Institute Of Medicine (IOM), Tribhuvan University (TU), thus it is following the community oriented, integrated teaching/ learning curriculum of MBBS programme of the university. The integrated basic medical science teaching is of two years duration (first and second year MBBS).

Vision of the department

•To provide international standard quality pharmacology/clinical pharmacology education to students from inside and outside the country.
•To be a recognized and distinguished unit in the field of clinical pharmacology by imparting the understanding of the principles of clinical pharmacology and therapeutics to future doctors.
•To educate and train medical undergraduates to prescribe rationally and to carry out basic research in the field of clinical pharmacology.
•To encourage students to participate in national and international scientific gatherings to uplift their own clinical and drug related skills.
•To establish benchmark therapeutic drug monitoring laboratory and poisoning unit.

Goal of the department

•To start the postgraduate programme (MD clinical pharmacology) based on the curriculum of TU-IOM.
•To enforce the disciplines of pharmacology and therapeutics as an integral part in the medical sciences (basic and clinical).
•To lead pharmacology field in both educational and research aspects upto the flagship status in Nepal.
•To produce well-round professional and competent prescribers.

Objective of the department

•To enhance the teaching learning process for MBBS, BNS and BSc nursing students in integrative manner with basic medical sciences according to the TU-IOM curriculum.
•To train on rational prescribing based on WHO guidelines.
•To develop treatment guidelines including antibiotics in collaboration with hospital departments
•To provide clinical services like adverse drug reaction monitoring, therapeutic drug monitoring and drug information services to the prescribers and patient for utmost patient care.
•To provide bedside consultation and on call consultation for poisoning/drug overdose cases

Department informations

The department is located on the first floor of the NAIHS Basic Science complex. It has separate room for HOD and all faculties. Department has separate practical laboratory, research laboratory and museum with systemically arranged drugs and devices. It also comprises a conference room with computer, departmental library, demonstration room, tutorial/problem based learning (PBL) room, reception with office assistant and computer, and a pantry. There are seven full time faculties, one resource faculty and one administrative staff for the smooth functioning and running of the department.







Current activities

1.Academic activities

The department is currently involved in teaching MBBS, BNS and BSc nursing students. The department has developed separate practical manuals for the first and second year MBBS students according to the curriculum. The manual for the first year students provides the basic concepts in common drug dosage forms, therapeutic drug monitoring, measurement of plasma cholinesterase in organophosphate poisoning and the process of rational treatment. The manual for the second year students focuses on the process of rational prescribing and includes details on'P'drug concept, differences between' P' drug and 'P' treatment, how to write appropriate prescription, how to give information, instructions and warning to the patients ,pulmonary drug delivery devices and instruction for use of some common drug dosage forms.

2.Drug information /counseling unit

This unit provides drug information as and when required for the prescribers as well as to other staff and patients for promoting rational use of medicines. This improves the quality of patient care. Patient counseling is done in OPD hours by clinical pharmacologists and trained hospital pharmacists for improving patient compliance with more information on drugs and disease.

3.Drug and therapeutic committee & Hospital formulary

The department has representation in drug and therapeutic committee (DTC) at Shree Birendra Hospital.

4.Pharmacovigilance unit

The hospital is registered as a pharmacovigilance centre and this unit formally reports suspected adverse reactions to drugs to the international pharmacovigilance center via national center.

5.Research

The department is involved in research in the hospital setting as well as in the community to investigate different aspects of drug use including prescribing, dispensing, adverse effects etc.The department also encourages undergraduate students to undertake research projects under the aegis of Institutional Review Board.


Future Plans:

1.Post graduate teaching program

To train a candidate specialist in clinical pharmacology competent to teach pharmacology and therapeutics and to carry out research in clinical pharmacology. The post graduate programme will be conducted as per curriculum of TU-IOM. The programme will aim to produce trained clinical pharmacologist able to
•describe pharmacology of drugs, laws and regulations governing drugs, adverse drug reaction monitoring and reporting.
•carry out qualitative/quantitative analysis of drugs
•identify problems, design research protocol, analyze and communicate skills
•execute experiments, analyze and communicate results
•acquire basic administration and managerial skills to conduct educational programs in the department
•continue learning through continuing education and recent advances
•apply the principles of guide to good prescribing
•familiarize with the methodology to conduct clinical trials
•evaluate and manage patient with drug overdose and poisoning
•describe the goals and objectives of drug and therapeutic committee.


2.Therapeutic drug monitoring unit

Plasma level monitoring and interpretation of antiepileptics like phenytoin, carbamazepine and paracetamol (overdose) will provide immediate data for decision making. In addition plasma cholinesterase measurement will be included as organophosphate poisoning is common in this part of world.

3.Clinical toxicology unit

As toxicology is a specialized area, the clinical pharmacologists in the unit will provide bedside consultation and on call consultation for poisoning/drug overdose cases

4.Training unit

This unit will organize regular training on rational use of drugs to the hospital staff and postgraduate residents to promote the rational use of drugs. This will also publish standard treatment guidelines in collaboration with various hospital departments.

5.Drug and therapeutics bulletin

It will be published and disseminate to the hospital staff. The pharmacovigilance reports will also be published in the bulletin


Introduction of head of the department (HOD)



Professor Dr Kumud Kumar Kafle has joined as head of department in 2012. He had served as HOD in department of clinical pharmacology at Institute of Medicine for more than 30 years and also worked as Dean of the Institute of Medicine. He is the pioneer in the field of clinical pharmacology in Nepal. He has published several papers in national and international journals. He is actively involved in the upliftment of clinical pharmacology in Nepal.


Faculty List